Parameter
| Biomarker | MTHFR rs1800469 | Full name | Methylenetetrahydrofolate reductase gene polymorphism | Molecular Type | Nucleic acids (DNA polymorphism) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Susceptibility and risk prediction |
| Disease | Thyroid Dysfunction | Disease Subtypes | / | ||
| Organ | Systemic/Thyroid | Test Sample / Technology Platform | Whole blood (genotyping, PCR - RFLP) | ||
| Pathobiological Mechanisms | Effect of folic acid metabolism and lead to an elevated homocysteine, aggravating thyroid lesions | ||||
| Clinical Availability Status | T allele carriers JiaJian increased risk | ||||
| Notes and Dynamics | Interaction with TSH levels | ||||