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672

Parameter
Biomarker APOE E4 Full name Apolipoprotein E ε4 allele Molecular Type Nucleic acids (DNA polymorphism)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Susceptibility and prognosis
Disease Thyroid Dysfunction Disease Subtypes /
Organ Systemic/Thyroid Test Sample / Technology Platform Whole blood (genotyping, sequencing)
Pathobiological Mechanisms It affects lipid metabolism and oxidative stress, and is associated with thyroid dysfunction
Clinical Availability Status The E4 allele is associated with elevated TSH
Notes and Dynamics May be affected by adjusting the NO generation thyroid function

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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