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142

Parameter
Biomarker Cr Full name Creatinine Molecular Type Metabolites
Molecular Formula C₄H₇N₃O Molecular Weight 113.12 g/mol Core Functional Dimensions Renal function assessment, disease staging
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Blood ( routine biochemical tests )
Pathobiological Mechanisms Muscle metabolic waste is excreted through glomerular filtration, and elevated levels reflect reduced GFR.
Clinical Availability Status Clinical routine application
Notes and Dynamics Affected by muscle mass and diet, it is only suitable for the evaluation of middle and late CKD, and cannot identify early renal function injury.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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