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145

Parameter
Biomarker eGFR Full name Estimated Glomerular Filtration Rate Molecular Type Functional parameter
Molecular Formula Molecular Weight Core Functional Dimensions Diagnosis, staging and prognosis judgment
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Serum ( based on biochemical test results + formula calculation )
Pathobiological Mechanisms Through endogenous markers such as creatinine and cystatin C, combined with age, gender and other parameters, calculated by formulas ( such as CKD-EPI, Cockcroft-Gault ), glomerular filtration function is indirectly reflected.
Clinical Availability Status Clinical routine use ( core diagnostic indicators )
Notes and Dynamics CKD diagnostic criteria : GFR < 60 mL / min / 1.73 m 2 for 3 months ; the new CKD-EPI equation removes ethnic variables and reduces population bias ; it should be combined with the evidence of renal injury ( such as albuminuria ) to make a comprehensive judgment

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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