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146

Parameter
Biomarker DDN Full name Dendrin Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Early diagnosis, condition assessment
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine, kidney tissue ( immunohistochemistry, protein detection )
Pathobiological Mechanisms It is involved in the regulation of glomerular filtration barrier function. After injury, it is relocated to the podocyte nucleus, reflecting podocyte injury
Clinical Availability Status Research verification stage
Notes and Dynamics Its nuclear localization phenomenon can be used as a new marker for the progression of human glomerular disease, which is directly related to the degree of podocyte function damage.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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