Parameter
| Biomarker | NPHN | Full name | Nephrin | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Early diagnosis, condition assessment | ||
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, kidney tissue ( immunohistochemistry, protein detection ) | ||
| Pathobiological Mechanisms | The key components that constitute the glomerular filtration barrier are released into urine after injury, reflecting the destruction of glomerular structure. | ||||
| Clinical Availability Status | Research verification stage | ||||
| Notes and Dynamics | In the early detection of diabetic nephropathy, the sensitivity was significantly higher than that of microalbuminuria. ROC analysis showed that the probability of predicting diabetic nephropathy. | ||||