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148

Parameter
Biomarker PDCN Full name Podocin Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Early diagnosis and prognosis evaluation
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine, kidney tissue ( immunohistochemistry, protein detection )
Pathobiological Mechanisms Maintaining the integrity of glomerular filtration barrier, abnormal expression is positively correlated with the degree of glomerular injury.
Clinical Availability Status Research verification stage
Notes and Dynamics It is directly related to the severity of CKD and is a potential core marker for the detection of early diabetic nephropathy in patients with type 2 diabetes.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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