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149

Parameter
Biomarker PCX Full name Podocalyxin Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Early diagnosis, condition assessment
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine, kidney tissue ( immunohistochemistry, protein detection )
Pathobiological Mechanisms It is involved in the construction of glomerular filtration barrier, and is released into urine after injury, suggesting that glomerular function is impaired.
Clinical Availability Status Research verification stage
Notes and Dynamics The sensitivity and specificity of early diagnosis of diabetic nephropathy are better than those of microalbuminuria, which can accurately identify early podocyte injury.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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