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Parameter
Biomarker IgG Full name Immunoglobulin Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Early diagnosis, condition assessment
Disease Chronic Kidney Disease (CKD) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Urine, kidney tissue ( immunohistochemistry, protein detection )
Pathobiological Mechanisms Under normal circumstances, it is difficult to pass through the glomerular filtration barrier, and the increase in urine reflects the damage of the filtration barrier.
Clinical Availability Status Research verification stage
Notes and Dynamics Serum and urinary IgG levels are positively correlated with the severity of nephropathy, and can be used as an early identification index for idiopathic membranous nephropathy and diabetic nephropathy.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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