Parameter
| Biomarker | KIM-1 | Full name | Kidney injury molecule-1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Early diagnosis、Prognostic judgment、Condition monitoring | ||
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, blood ( protein detection, ELISA) | ||
| Pathobiological Mechanisms | It is involved in the repair of renal tubular injury. After injury, the expression of kidney is up-regulated and released into urine, reflecting renal tubular inflammation. | ||||
| Clinical Availability Status | Some clinical applications / Research verification stage | ||||
| Notes and Dynamics | In inflammatory nephropathy such as vasculitis and glomerulonephritis, it is significantly associated with decreased renal function ( ΔeGFR ) and can be used as a prognostic indicator for such nephropathy. | ||||