Parameter
| Biomarker | IL-18 | Full name | Interleukin-18 | Molecular Type | Cytokine |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Early diagnosis、Condition monitoring | ||
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, blood ( protein detection, ELISA) | ||
| Pathobiological Mechanisms | Mediated renal tubular inflammatory response, increased release after injury, and promoted renal interstitial fibrosis. | ||||
| Clinical Availability Status | Some clinical applications / Research verification stage | ||||
| Notes and Dynamics | It was negatively correlated with renal uric acid excretion. The lower the 24-hour urinary uric acid level, the higher the urinary IL-18 / creatinine ratio, which could indirectly reflect the degree of renal tubular injury. | ||||