Parameter
| Biomarker | UMOD | Full name | Uromodulin | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Early diagnosis、Prognostic judgment | ||
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, blood ( protein detection, ELISA) | ||
| Pathobiological Mechanisms | It is secreted by renal tubular ascending branch cells and is positively correlated with glomerular filtration rate ( GFR ). | ||||
| Clinical Availability Status | Some clinical applications / Research verification stage | ||||
| Notes and Dynamics | Low levels suggest an increased risk of CKD progression, which can identify early CKD with traditional creatinine ' blind spot '.ROC analysis can distinguish patients with CKD stage 0 and stage I. | ||||