Parameter
| Biomarker | VNN1 | Full name | Vanin 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Early diagnosis、Condition monitoring | ||
| Disease | Chronic Kidney Disease (CKD) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Urine, blood ( protein detection, ELISA) | ||
| Pathobiological Mechanisms | It is involved in the regulation of oxidative stress in renal tubules, and the expression is up-regulated after injury, reflecting the dysfunction of renal tubules. | ||||
| Clinical Availability Status | Some clinical applications / Research verification stage | ||||
| Notes and Dynamics | The level of urinary Vanin 1 in hypertensive patients is negatively correlated with eGFR and positively correlated with urinary protein creatinine ratio, which is a potential marker of hypertension-related CKD. | ||||