Parameter
| Biomarker | ITIH5 gene promoter methylation | Full name | Inter-α-trypsin inhibitor heavy chain 5 gene promoter methylation | Molecular Type | Nucleic acid (DNA methylation) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Early non-invasive diagnosis |
| Disease | Bladder Cancer (BC) | Disease Subtypes | / | ||
| Organ | Bladder | Test Sample / Technology Platform | Urine (qMSP, dPCR) | ||
| Pathobiological Mechanisms | Tumour-suppressor; methylation detectable in urine cfDNA; combinatorial assay increases performance | ||||
| Clinical Availability Status | Research verification stage | ||||
| Notes and Dynamics | Combined EI-BLA test reaches 64–70 % sensitivity & 97 % specificity | ||||