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212

Parameter
Biomarker NOX4 Full name NADPH Oxidase 4 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis & prognosis
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Tissue (qRT-PCR, IHC)
Pathobiological Mechanisms Interacts with SH3YL1; significantly up-regulated in MIBC vs NMIBC; drives invasion-related processes
Clinical Availability Status Research verification stage
Notes and Dynamics Important for MIBC aggressiveness; mechanistic exploitation ongoing

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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