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216

Parameter
Biomarker CDKN2A, CTSV, FOXM1 Full name Cyclin-dependent kinase inhibitor 2A,Cathepsin V,Forkhead box M1 Molecular Type Nucleic acid (mRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, prognosis & progression prediction
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Tissue (qRT-PCR, bioinformatics)
Pathobiological Mechanisms Combined signature shows 95.5 % sensitivity & 100 % specificity for progression; involved in tumour-related biology
Clinical Availability Status Research verification stage
Notes and Dynamics Multi-gene panel improves prognostic accuracy; clinical implementation pending

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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