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222

Parameter
Biomarker Ascore (4-gene anoikis-related signature) Full name Ascore (4-gene anoikis-related signature) Molecular Type Nucleic acid (mRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis & immunotherapy-response prediction
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Tissue, CTCs (RNA-seq, database validation)
Pathobiological Mechanisms Independent prognostic factor; superior to TMB or PD-L1 for predicting immunotherapy response
Clinical Availability Status Research verification stage
Notes and Dynamics Multi-gene signature integrating anoikis; ready for external validation

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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