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224

Parameter
Biomarker SPP1 Full name Secreted Phosphoprotein 1 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis & immune-infiltration modulator
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Tissue (IHC, microarray, database)
Pathobiological Mechanisms Early differential expression; poor prognosis; correlates with immune-cell infiltration & checkpoint genes
Clinical Availability Status Research verification stage
Notes and Dynamics Links pathology & immune micro-environment; candidate for combination therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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