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230

Parameter
Biomarker PTGDS Full name Prostaglandin D2 Synthase Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Urine (reverse-phase nano-LC-MS/MS)
Pathobiological Mechanisms Down-regulated in BC urine; 100 % specificity, 81 % sensitivity for BC detection
Clinical Availability Status Research verification stage
Notes and Dynamics High-specificity urine protein marker; requires validation in multicenter cohorts

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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