Parameter
| Biomarker | lncRNA PVT1 / miR-194-5p / BCLAF1 axis | Full name | Long non-coding RNA PVT1 / MicroRNA-194-5p / BCL2 Associated Transcription Factor 1 axis | Molecular Type | lncRNA, miRNA, Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis & therapeutic target |
| Disease | Bladder Cancer (BC) | Disease Subtypes | / | ||
| Organ | Bladder | Test Sample / Technology Platform | Tissue & cells (qRT-PCR, Western blot, luciferase reporter) | ||
| Pathobiological Mechanisms | PVT1 acts as ceRNA sponging miR-194-5p to up-regulate BCLAF1; promotes proliferation, migration, invasion & EMT | ||||
| Clinical Availability Status | Research verification stage | ||||
| Notes and Dynamics | lncRNA-miRNA-mRNA regulatory axis; dual diagnostic & therapeutic implications | ||||