Parameter
| Biomarker | TWIST1 | Full name | Twist Family BHLH Transcription Factor 1 | Molecular Type | Transcription factor |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis & therapeutic target |
| Disease | Bladder Cancer (BC) | Disease Subtypes | / | ||
| Organ | Bladder | Test Sample / Technology Platform | Tissue (qRT-PCR) | ||
| Pathobiological Mechanisms | Over-expression correlates with advanced stage, high grade & poor prognosis; low expression associated with longer disease-free survival; promoter methylation does not affect expression | ||||
| Clinical Availability Status | Research verification stage | ||||
| Notes and Dynamics | EMT-related transcription factor; independent prognostic & therapeutic target | ||||