Parameter
| Biomarker | circPSMA7 (hsa_circ_0003456, N6-methyl-adenosine-modified) | Full name | circular RNA proteasome 20S subunit alpha 7 (hsa_circ_0003456, N6-methyladenosine-modified) | Molecular Type | Circular RNA (with epigenetic modification) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Therapeutic target & tumor-malignancy regulator |
| Disease | Bladder Cancer (BC) | Disease Subtypes | / | ||
| Organ | Bladder | Test Sample / Technology Platform | Tissue & cells (qRT-PCR, circRNA-seq) | ||
| Pathobiological Mechanisms | N6-methyl-adenosine-modified circPSMA7 is over-expressed in BCa and enhances malignancy via the miR-128-3p/MAPK1 axis | ||||
| Clinical Availability Status | Research verification stage: epigenetic modification and regulatory mechanism defined; clinical validation needed | ||||
| Notes and Dynamics | Epigenetically modified circRNA providing a novel therapeutic target for BCa | ||||