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Parameter
Biomarker SNCA Full name Synuclein Alpha Molecular Type Protein & nucleic acid (DNA methylation)
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis & immune-infiltration regulation
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Tissue (database analysis; exact assay not specified)
Pathobiological Mechanisms Down-regulated in BLCA; inversely correlated with DNA methylation; high expression is an independent prognostic risk factor and participates in T-cell infiltration
Clinical Availability Status Research verification stage: links methylation, prognosis and immune infiltration; clinical validation required
Notes and Dynamics Alpha-synuclein gene providing prognostic and immunological insights for BLCA

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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