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262

Parameter
Biomarker CUBN / MPO Full name Cubilin Protein / Myeloperoxidase Protein ratio Molecular Type Protein (ratio)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis & prognosis (combined ratio)
Disease Bladder Cancer (BC) Disease Subtypes /
Organ Bladder Test Sample / Technology Platform Urine (immunoblot, ELISA)
Pathobiological Mechanisms Low CUBN/MPO ratio predicts high-grade BC recurrence & progression risk
Clinical Availability Status Research verification stage (n = 30 pilot)
Notes and Dynamics Ratio-based prognostic index; large-scale validation needed to avoid sampling bias

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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