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265

Parameter
Biomarker VEGF Full name Vascular endothelial growth factor Molecular Type Protein(Cytokines / Angiogenic factors)
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis、Prediction of treatment response
Disease Renal Cell Carcinoma(RCC) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Serum(ELISA)
Pathobiological Mechanisms Regulating RCC angiogenesis is the core target of VEGF-targeted therapy
Clinical Availability Status Clinical validation/Routine application: Included in multiple clinical trial prognostic assessments; partially utilized for monitoring the efficacy of targeted therapy
Notes and Dynamics Patients with high baseline VEGF levels may benefit more from sorafenib therapy; associated with tumor invasion and metastasis

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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