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273

Parameter
Biomarker ctDNA Full name Circulating tumor DNA Molecular Type Nucleic acid(DNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, monitoring, and prediction of treatment response
Disease Renal Cell Carcinoma(RCC) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Peripheral blood (targeted sequencing)
Pathobiological Mechanisms Genomic fragments released into the bloodstream by tumor cells reflect the genomic characteristics of the tumor.
Clinical Availability Status Study test / Frontier exploration: Dynamic monitoring of tumor burden and treatment resistance
Notes and Dynamics Detection of gene mutations such as VHL and BAP1, with post-treatment decline indicating efficacy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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