Parameter
| Biomarker | CSF1、ICAM1、IL-18BP、KIM1、TNFRII | Full name | Colony Stimulating Factor 1 / Intercellular Adhesion Molecule 1 / Interleukin-18 Binding Protein / Kidney Injury Molecule 1 / Tumor Necrosis Factor Receptor II composite biomarker score | Molecular Type | Protein combination |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Predicting treatment response |
| Disease | Renal Cell Carcinoma(RCC) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Serum(Multivariate detection platform) | ||
| Pathobiological Mechanisms | Covering multiple pathways including inflammation and angiogenesis, it comprehensively reflects the biological characteristics of tumors. | ||||
| Clinical Availability Status | Study test: Validation in the RECORD-3 trial | ||||
| Notes and Dynamics | Specific prediction of therapeutic benefit with everolimus, significantly longer PFS in patients with high CBS | ||||