Parameter
| Biomarker | VHL gene | Full name | von Hippel-Lindau gene | Molecular Type | Nucleic acid（DNA） |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, classification, susceptibility |
| Disease | Renal Cell Carcinoma(RCC) | Disease Subtypes | / | ||
| Organ | Kidney | Test Sample / Technology Platform | Tissue / Whole Blood (Genomic Sequencing) | ||
| Pathobiological Mechanisms | ccRCC core driver gene, mutations leading to 3p deletion and VHL protein inactivation | ||||
| Clinical Availability Status | clinically available / essential for classification: auxiliary indicators for pathological classification | ||||
| Notes and Dynamics | Patients with VHL syndrome present with bilateral multiple ccRCC; associated with 3p deletion | ||||