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278

Parameter
Biomarker PAX8 Full name Paired Box 8 Molecular Type Protein(Transcription factor)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis (subtyping / metastasis tracing)
Disease Renal Cell Carcinoma(RCC) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Organization (Immunohistochemistry)
Pathobiological Mechanisms Renal tissue-specific transcription factor, marker of renal tumors
Clinical Availability Status Clinically available / Routine pathology: Core markers for tracing metastatic foci
Notes and Dynamics The sensitivity is higher than that of PAX2, and high-grade tumors may be negative; angiosmooth muscle lipoma may be negative.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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