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283

Parameter
Biomarker MET Full name Molecular Type Molecular Type Nucleic acid(DNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis (Classification)
Disease Renal Cell Carcinoma(RCC) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Tissue / Whole Blood (Genomic Sequencing)
Pathobiological Mechanisms Core driver gene of type I pRCC, mutations lead to pathway activation
Clinical Availability Status Study test / Typing assistance: Characteristics of hereditary papillary renal cell carcinoma
Notes and Dynamics Type I pRCC commonly exhibits amplifications of chromosomes 7p and 17p, as well as deletions of the Y chromosome.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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