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294

Parameter
Biomarker TFE3、TFEB gene Full name Transcription Factor Binding to IGHM Enhancer 3、Transcription Factor EB Molecular Type Nucleic acid(DNA / Fusion gene)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis
Disease Renal Cell Carcinoma(RCC) Disease Subtypes /
Organ Kidney Test Sample / Technology Platform Tissue(FISH / genesequencing)
Pathobiological Mechanisms Transcription factor fusion drives tumorigenesis
Clinical Availability Status Clinically available / Pathologically confirmed: Gold standard
Notes and Dynamics Immunohistochemistry can assist in screening, but final confirmation requires gene testing.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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