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Parameter
Biomarker CRP Full name C-reactive protein Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prediction
Disease PCOS Disease Subtypes /
Organ Ovary Test Sample / Technology Platform Serum (immunoturbidimetry, ELISA)
Pathobiological Mechanisms PCOS exhibits the characteristic of "chronic low-level inflammation". Inflammatory factors activate the local inflammatory response in adipose tissue and the ovary, promoting insulin resistance and androgen synthesis. CRP is a sensitive indicator reflecting systemic inflammation.
Clinical Availability Status Clinical auxiliary assessment: Often used for risk stratification of metabolic complications in PCOS patients.
Notes and Dynamics The serum CRP levels in patients with PCOS are mostly slightly elevated (typically < 10mg/L), and are positively correlated with insulin resistance and abdominal obesity. A CRP level of ≥ 3mg/L indicates an increased risk of metabolic syndrome, and lifestyle intervention should be strengthened.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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