Parameter
| Biomarker | miR-146a | Full name | MicroRNA-146a | Molecular Type | Nucleic acid（microRNA） |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | Cervical Cancer | Disease Subtypes | / | ||
| Organ | Cervix | Test Sample / Technology Platform | Serum / Tumor Tissue (RT-PCR, Small RNA Sequencing, Chip Technology) | ||
| Pathobiological Mechanisms | Regulating the TLR/NF-κB inflammatory pathway and tumor suppressor genes (such as BRCA1), high expression promotes tumor proliferation and immune escape. | ||||
| Clinical Availability Status | Frontier Research: Currently exploring as a target for predicting prognosis and treatment response. | ||||
| Notes and Dynamics | Frontier Research: Studies are currently exploring miR-146a, which is a potential target for predicting prognosis and treatment response. In patients with high expression of miR-146a, the 5-year recurrence rate is 42%, significantly higher than that of the low-expression group (15%). It can also serve as a combined target for immunotherapy. | ||||