Parameter
| Biomarker | OPN | Full name | Osteopontin | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis, prediction |
| Disease | Cervical Cancer | Disease Subtypes | / | ||
| Organ | Cervix | Test Sample / Technology Platform | Serum / Tumor Tissue (RT-PCR, Small RNA Sequencing, Chip Technology) | ||
| Pathobiological Mechanisms | It mediates cell adhesion, angiogenesis and matrix remodeling, and its high expression enhances the invasion and distant metastasis ability of tumor cells. | ||||
| Clinical Availability Status | Research validation stage: Core candidate for transfer-related prognostic markers. | ||||
| Notes and Dynamics | The serum OPN level was positively correlated with lymph node metastasis and vascular invasion in cervical cancer (r = 0.63, P < 0.001); blocking OPN could inhibit tumor metastasis. | ||||