Parameter
| Biomarker | CA-125 | Full name | Cancer antigen 125 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Monitoring |
| Disease | Ovarian Cancer | Disease Subtypes | / | ||
| Organ | Ovary | Test Sample / Technology Platform | Serum (ELISA, CLIA, electrochemiluminescence immunoassay) | ||
| Pathobiological Mechanisms | Ovarian cancer cells show high expression, participating in the adhesion, invasion and peritoneal metastasis of tumor cells. The tumor burden is positively correlated with the serum level. | ||||
| Clinical Availability Status | Clinical routine application: As a core indicator for efficacy monitoring and recurrence warning, it has been included in clinical treatment guidelines. | ||||
| Notes and Dynamics | The early diagnosis has a low sensitivity. Benign diseases (endometriosis, pelvic inflammatory disease) are prone to false positives. It is often combined with HE4 for detection to enhance the efficacy of early diagnosis. | ||||