Parameter
| Biomarker | GLUT1 | Full name | Glucose transporter 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis |
| Disease | Breast Cancer | Disease Subtypes | / | ||
| Organ | Breast | Test Sample / Technology Platform | Tumor tissue (IHC, PET-CT: functional imaging) | ||
| Pathobiological Mechanisms | GLUT1 is a key protein for glucose transmembrane transport. Tumor cells highly express GLUT1 to enhance glucose uptake, meeting the energy demands for rapid proliferation. | ||||
| Clinical Availability Status | Research verification: High expression of GLUT1 is associated with poor prognosis of breast cancer and can serve as a metabolic treatment target. | ||||
| Notes and Dynamics | GLUT1 inhibitors (such as STF-31) when used in combination with chemotherapy and immunotherapy, have shown a synergistic anti-tumor effect in preclinical models. | ||||