Parameter
| Biomarker | GRP | Full name | Gastrin-releasing peptide | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | Breast Cancer | Disease Subtypes | / | ||
| Organ | Breast | Test Sample / Technology Platform | Tumor tissues (IHC, radioimmunoassay RIA) | ||
| Pathobiological Mechanisms | GRP is a neuropeptide hormone. In some breast cancers (especially the neuroendocrine subtype), GRP is highly expressed. It promotes cell proliferation and metastasis by binding to the GRP receptor. | ||||
| Clinical Availability Status | Research verification: GRP testing is used for the diagnosis of neuroendocrine subtypes of breast cancer, and drugs targeting the GRP receptor are in preclinical research. | ||||
| Notes and Dynamics | The combined detection of GRP with other neuroendocrine markers (such as Syn and CgA) can enhance the accuracy of neuroendocrine subtype diagnosis. | ||||