Parameter
| Biomarker | CA-125 | Full name | Cancer antigen 125 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, monitoring, prognosis |
| Disease | Endometrial Cancer | Disease Subtypes | / | ||
| Organ | Endometrium | Test Sample / Technology Platform | Serum / Plasma (ELISA, CLIA) | ||
| Pathobiological Mechanisms | Abnormally highly expressed during tumor progression, it participates in tumor cell invasion, adhesion and angiogenesis. Its level is related to the tumor burden. | ||||
| Clinical Availability Status | Clinically commonly used (routine test): Widely used for postoperative monitoring and recurrence warning; combined with HE4 can enhance the efficacy of early diagnosis. | ||||
| Notes and Dynamics | A single indicator has insufficient sensitivity for patients in stage I. Benign gynecological diseases (such as pelvic inflammation) may lead to false positives. | ||||