Parameter
| Biomarker | CA-125 | Full name | Cancer antigen 125 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Monitoring |
| Disease | Endometriosis | Disease Subtypes | / | ||
| Organ | Ovary/Endometrium | Test Sample / Technology Platform | Serum (ELISA, CLIA) | ||
| Pathobiological Mechanisms | It reflects the damage of body cavity epithelial cells or the activation of inflammation. It can also be expressed in ectopic endometrial tissues, but its specificity is limited. | ||||
| Clinical Availability Status | It is mainly used for auxiliary diagnosis and postoperative monitoring, but has low sensitivity for early-stage lesions. | ||||
| Notes and Dynamics | It is often used in combination with HE4 (ROMA index) to enhance the diagnostic specificity for endometriosis cysts in the ovaries. | ||||