Parameter
| Biomarker | NGF | Full name | Nerve growth factor | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis |
| Disease | Endometriosis | Disease Subtypes | / | ||
| Organ | Endometrium/Ectopic lesions | Test Sample / Technology Platform | Endometrium/Ectopic lesions | ||
| Pathobiological Mechanisms | Promotes the generation and sensitization of nerve fibers, and is positively correlated with the severity of pain; is highly expressed in ectopic lesions. | ||||
| Clinical Availability Status | In the process of translating research into clinical practice: There are already commercial ELISA reagents available; they are used for pain classification and the selection of therapeutic targets. | ||||
| Notes and Dynamics | Anti-NGF therapies (such as entrectinib) have shown in animal experiments to be able to alleviate the pain associated with endometriosis. | ||||