Parameter
| Biomarker | cfDNA methylation | Full name | Cell-free DNA methylation | Molecular Type | Nucleic acid |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | Endometriosis | Disease Subtypes | / | ||
| Organ | Endometrium | Test Sample / Technology Platform | Plasma/ menstrual blood (methylated PCR, NGS) | ||
| Pathobiological Mechanisms | High methylation of genes such as HOXA10 and ESR1 leads to dysfunction of the endometrium and promotes the growth of ectopic tissues. | ||||
| Clinical Availability Status | Frontier Research: Possesses potential for non-invasive screening, multiple markers have a high detection rate in early-stage patients | ||||
| Notes and Dynamics | A multi-gene panel based on cfDNA methylation characteristics is currently under development. | ||||