Parameter
| Biomarker | 8-iso-PG | Full name | 8-isoprostaglandin | Molecular Type | Lipid |
|---|---|---|---|---|---|
| Molecular Formula | C20H32O5 | Molecular Weight | 352.47 g/mol | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | BPH | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Urine (ELISA) | ||
| Pathobiological Mechanisms | It is a specific and stable marker of lipid peroxidation, which is non-enzymatically produced by the free radical catalyzed from the arachidonic acid in the cell membrane phospholipid. It directly reflects the tissue oxidative damage caused by BPH. | ||||
| Clinical Availability Status | Research verification | ||||
| Notes and Dynamics | It is regarded as the gold standard biomarker of oxidative stress. It is significantly decreased after treatment in BPH patients, which is associated with the relief of obstruction. | ||||