Parameter
| Biomarker | 8-OHdG | Full name | 8-hydroxydeoxyguanosine | Molecular Type | Nucleic acid (products of oxidative DNA damage) |
|---|---|---|---|---|---|
| Molecular Formula | C10H13N5O5 | Molecular Weight | 283.24 g/mol | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | BPH | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Urine (ELISA) | ||
| Pathobiological Mechanisms | The product formed when guanosine is hydroxylated after reactive oxygen species attack DNA molecules, reflecting genetic material damage caused by oxidative stress. | ||||
| Clinical Availability Status | Research verification | ||||
| Notes and Dynamics | It is widely used in the assessment of various diseases related to oxidative stress. In this study, although no significant difference was found in baseline levels, it remains an important indicator. | ||||