Parameter
| Biomarker | PSA | Full name | Prostate-Specific Antigen | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | BPH | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Serum (ELISA; Radioimmunoassay) | ||
| Pathobiological Mechanisms | KLK3 is one of the most potent targets of androgen receptor (AR) in the prostate. Overactivation of the androgen signaling pathway ultimately leads to positive transcriptional regulation of KLK3 and the production of prostate-specific antigen (PSA). | ||||
| Clinical Availability Status | Clinical routine | ||||
| Notes and Dynamics | PSA testing is not specific enough and further monitoring is needed. | ||||