Parameter
| Biomarker | CD44 | Full name | Cluster of Differentiation 44 | Molecular Type | Glycoprotein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | BPH | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Tissue samples (immunohistochemistry, IHC) | ||
| Pathobiological Mechanisms | It is involved in cell adhesion, migration, differentiation and signal transduction. As a metastasis suppressor gene, its down-regulation promotes cell detachment from basement membrane and enhances invasiveness. Promoter methylation may lead to down-regulation of expression. | ||||
| Clinical Availability Status | In the research phase, not yet routinely used in clinical practice | ||||
| Notes and Dynamics | Multicenter large-sample studies and longitudinal data validation are required | ||||