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362

Parameter
Biomarker FLNA Full name Filamin A Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis
Disease BPH Disease Subtypes /
Organ Prostate Test Sample / Technology Platform Serum samples (IP-MRM mass spectrometry technology)
Pathobiological Mechanisms It participates in cytoskeletal remodeling, integrin signaling pathway, and metastasis process, and its cleavage fragments may be associated with tumor progression and invasiveness.
Clinical Availability Status In the research phase, it has demonstrated good diagnostic performance
Notes and Dynamics Eliminating prostate volume measurement streamlines the testing process. As a complementary PSA test, it reduces unnecessary biopsies and is being developed into a multiparameter blood test tool.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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