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365

Parameter
Biomarker CDK5RAP2 Full name CDK5 Regulatory Subunit Associated Protein 2 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, distinguish
Disease BPH Disease Subtypes /
Organ Prostate Test Sample / Technology Platform Serum (DIA-MS, ELISA)
Pathobiological Mechanisms It regulates cell cycle and centrosome formation, and is overexpressed in BPH to promote the proliferation of prostate cells.
Clinical Availability Status Verified in research phase
Notes and Dynamics Machine learning screening with AUC=0.900 shows promise as a complementary diagnostic marker for PSA

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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