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702

Parameter
Biomarker MEHHP Full name Mono(2-ethyl-5-hydroxyhexyl) phthalate (metabolite of PAEs) Molecular Type Environmental pollutants metabolites
Molecular Formula C₁₆H₂₂O₅ Molecular Weight 294.34 Core Functional Dimensions Risk prediction
Disease Thyroid Cancer Disease Subtypes /
Organ Thyroid Test Sample / Technology Platform Urine (HPLC/MS/MS, UPLC/MS/MS)
Pathobiological Mechanisms Cut the NIS expression, interfere with the iodine metabolism and hormone synthesis
Clinical Availability Status Study phase: positively related to the FTC risk, AUC 0.54
Notes and Dynamics Joint to other PAEs metabolites improve predictive value

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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