Parameter
| Biomarker | RET | Full name | RET gene mutation | Molecular Type | Nucleic acid (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Diagnosis, susceptibility, therapeutic targets |
| Disease | Thyroid Cancer | Disease Subtypes | / | ||
| Organ | Thyroid | Test Sample / Technology Platform | Whole blood/tissue (NGS, Sanger sequencing) | ||
| Pathobiological Mechanisms | Activate the RET signaling pathways, and promote the proliferation of tumor cells | ||||
| Clinical Availability Status | Hereditary MTC clinical routine application: 70% - 90%, 40% 60% sporadic MTC checked out | ||||
| Notes and Dynamics | Guide RET inhibitor treatment, familial MTC genetic counseling | ||||