Parameter
| Biomarker | PSA | Full name | Prostate-Specific Antigen | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Susceptibility, diagnosis |
| Disease | PCa | Disease Subtypes | / | ||
| Organ | Prostate | Test Sample / Technology Platform | Serum (ELISA; RIA) | ||
| Pathobiological Mechanisms | KLK3 is one of the most potent targets of androgen receptor (AR) in prostate, and the overactivation of androgen signaling pathway leads to the positive transcriptional regulation of KLK3 and the production of PSA. | ||||
| Clinical Availability Status | Clinical routine | ||||
| Notes and Dynamics | PSA testing has insufficient specificity and a high probability of false positives, requiring further monitoring. | ||||